- A Cross-sectional Study on the Risk Factors Related to Fatty Liver.
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S H Ohm, B C Yoo, S J Kim, C U Lee, K T Pai, S C Kim, H R Shin
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Korean J Prev Med. 1993;26(2):179-191.
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- Generally fatty liver is attributed either to chronic alcoholism, diabetes mellitus, or obesity. Based upon this commonly held clinical brief, this study was conducted to investigate the contributing factors of fatty liver and odds ratio (OR) of known contributing factors. A sample of 310 male participants, who visited at Seoul Paik Automated Multiphasic Health Testing System from November 1991 to December 1991, was separated into 112 cases and 198 controls by ultrasonographic finding. There were statistically significant difference between fatty liver and normal in triglyceride(TG), body mass index(BMI), alanine aminotransferase(ALT), high density lipoprotein cholesterol (HDL-C), fasting blood sugar (FBS), alcohol consumption, low density lipoprotein cholesterol (LDL-C), total cholesterol, gamma-glutamyl transferase (gamma-GT), duration of alcohol intake and alkaline phospahtase (Alk.P)(P<0.01, P<0.05). The statistically significant elevated odds ratio were noted for TG (4.48, confidence interval (CI) 2.66-7.55, P=0.000), alcohol consumption(3.24, CI 1.56-6.23, P=0.002), BMI(3.05, CI 1.87-4.97, P=0.000), and FBS(2.59, CI 1.53-4.40, P=0.000). In summary, it is suggested that the fatty liver could be preventive by avoiding such deleterious factors as high fat diet, alcohol and obesity.
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Summary
- The Type of Anemia in Organic Solvent Workers by MCV and RDW.
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S J Kim, S H Ohm, D H Kim, C U Lee, J H Chun, S C Kim, K T Pae
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Korean J Prev Med. 1992;25(2):162-171.
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- The hematologic effect by low-concentration and repeated exposure to mixed organic solvent remains obscure. This study was performed to evaluate the hematologic effect by mixed organic solvent exposure, especially on the type of anemia by mean corpuscular volume(MCV) and red blood cell distribution width(RDW). The subject were 64 organic solvent workers(male 4, female 60) and 78 general workers(male 18, female 60) who showed anemic tendency in worker's health examination which carried out by Pusan Paik Hospital from January to December, 1988. The author gained some hematologic findings (hemoglobin, hematocrit, RBC, WBC, MCV, MCHC, platelet count, ESR, RDW) from auto-analysis method by coulter counter S plus IV, and compared the type of anemia by MCV and RDW. In the pilot study for estimating the prevalence of anemia according to the type of job, the prevalence rate was higher in organic solvent workers than in public officials as 10.9% and 4.1% respectively. There were statistical significance in the value of hemoglobin, hematocrit, MCV, MCHC, platelet count, ESR, RDW between the two study groups with more severe anemic tendency in organic solvent workers. The type of anemia in organic solvent workers was microcytic and anisocytic with the mean value of 68.28+/-8.3fL of MCV and 19.1+/-4.0% of RDW.
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Summary
- Hematologic Findings and Urinarysis of Workers Exposed to Mixed Organic Solvents.
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K W Jeong, D H Kim, S H Ohm, S J Kim, J H Kim, S S Moon, J H Chun, Y W Kim
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Korean J Prev Med. 1991;24(3):314-337.
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- To evaluate the effects on health by exposure to mixed organic solvents, the author analyzed some labortory findings of blood(hemoglobin, hematocrit, RBC, WBC, SGOT, SGPT) and urine(protein, blood, sugar) that were obtained from 722 workers (male: 446, female: 276) who worked in plywood, painting and shoes factories in Pusan area from January to December, 1990. The result were as follows; 1. The mean values of each hematologic finding were all within normal limit but there were significant differences at hematocrit, RBC, WBC, SGOT, in male and at WBC, SGPT in female at the comparison of the mean values and the distribution according to the normal criteria by type of work. 2. There were no differences in urinalysis (protein, blood, sugar) by type of work. 3. In stepwise multiple regression, analysis of hematologic findings on age, working duration and type of work, regression coefficients on age and type of work were relatively high in male and female subject, respectively. As a result of this study, it is considered that the measurement of WBC with morphology is significant in hematologic findings and instead of spot urine and urinstix, 24 hours urine and quantitative analysis is required in urinalysis in screening test for healthy status of workers who deal with the organic solvents.
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